What is Primary Sclerosing Cholangitis (PSC)?
In Primary Sclerosing Cholangitis (PSC) the bile ducts both inside and outside the liver become inflamed which can cause them to narrow. This in turn can interrupt the flow of bile and cause it to build up in the liver which then causes inflammation. Over time the inflammation can cause fibrosis and cirrhosis.
80% of PSC patients also have inflammatory bowel disease.
There is currently no cure for PSC. If PSC causes liver failure then a transplant will be required. However, many people with PSC live full lives without ever needing a transplant.